The HPE ProLiant Compute DL380a Gen12 is built for enterprises at the forefront of AI, high-performance computing (HPC), and data-intensive workloads. Featuring a dual-socket 4U rack design optimized for GPU acceleration, it delivers exceptional scalability, robust security, and cutting-edge performance to power the next generation of enterprise applications. The DL380a Gen12 is now available at Saitech, enabling organizations to deploy advanced AI and HPC infrastructure without delay.
Core Performance and GPU Acceleration
The HPE ProLiant DL380a Gen12 leverages dual Intel Xeon 6 processors, each supporting up to 144 cores within a 250W TDP, delivering the raw compute power required for intensive tasks such as AI inference, advanced virtualization, and large-scale data analytics.
Engineered for GPU acceleration, the server supports up to 10 double-wide GPUs, each rated at 600W, providing exceptional density for parallel processing. For workloads requiring extreme performance, support for NVIDIA 4-way NVLink bridges enables ultra-fast GPU-to-GPU communication, significantly accelerating AI training and deep learning workloads.
High-Capacity Memory and Flexible Expansion
The DL380a Gen12 supports up to 32 DDR5 DIMMs (16 per processor), delivering up to 4 TB of memory at speeds up to 6400 MT/s, ensuring high bandwidth and low latency for compute-intensive workloads.
For expansion and connectivity, the server includes six PCIe Gen5 x16 slots and two OCP 3.0 mezzanine slots, providing flexible options for high-speed networking, storage, and accelerators.
Built-In Security for Modern Threats
Built on HPE’s Silicon Root of Trust, the DL380a Gen12 establishes a zero-trust security foundation by validating firmware integrity before system boot, protecting against firmware-level attacks.
The platform also integrates Intel SGX and Boot Guard for secure execution environments and enhanced data protection. Automated firmware recovery enables rapid restoration to a trusted state if a compromise is detected.
AI-Driven Management and Cloud Integration
The DL380a Gen12 delivers cloud-native management capabilities through HPE GreenLake and HPE Compute Ops Management, enabling AI-driven automation, simplified provisioning, and efficient lifecycle management across hybrid and private cloud environments.
Optimized Power and Cooling Architecture
The server features a multi-domain power architecture with three independent power domains, two dedicated to GPUs, and supports up to six power supplies for maximum redundancy and reliability.
Its 4U chassis is engineered with optimized airflow and thermal design to support high-density GPU configurations while maintaining consistent performance under sustained workloads.
Transforming Workloads with AI and HPC
The HPE ProLiant Compute DL380a Gen12 is purpose-built for workloads that demand extreme compute and GPU acceleration, including:
- Generative AI model inference
- Visual computing and 3D modeling
- Digital twin environments
- Private cloud and hybrid deployments
- Machine learning and deep learning workloads
Why the DL380a Gen12 Redefines Enterprise Compute
The DL380a Gen12 distinguishes itself by combining massive GPU scalability, robust compute power, advanced memory capabilities, and enterprise-grade security within a cloud-native architecture. Designed with modern workloads in mind, it is tailored for organizations embracing AI, high-performance computing (HPC), and large-scale data-driven applications, ensuring performance and reliability at enterprise scale.
Available Soon at Saitech
The HPE ProLiant Compute DL380a Gen12 is now available at Saitech. Contact us today for custom GPU configurations, AI-ready solutions, and enterprise deployment support tailored to your workloads.

