As data-intensive workloads continue to expand, organizations need server solutions that provide the right combination of compute power, memory capacity, and storage flexibility. The HPE ProLiant Compute DL345 Gen12 is designed to meet these demands, delivering strong performance, energy efficiency, and scalability in a 2U, single-socket form factor.
Built on the 5th Generation AMD EPYC™ processor family, the DL345 Gen12 supports up to 192 cores and 6 TB of DDR5 memory, making it an excellent choice for virtualization, data analytics, AI inference, and enterprise applications. With its flexible configuration options, including support for up to 36 EDSFF E3.S drives, multiple GPUs, and PCIe Gen5 I/O, this server provides the versatility needed to handle modern compute and storage challenges efficiently.
Key Features & Specifications of HPE ProLiant Compute DL345 Gen12
Processor and Architecture
The DL345 Gen12 is powered by 5th Generation AMD EPYC™ processors from the 9004 Series, offering exceptional core density and energy efficiency. With support for up to 192 cores per socket, this server delivers powerful single-socket performance capable of handling multi-threaded and high-throughput applications. The single-socket architecture also helps lower software licensing costs, making it a cost-effective choice for virtualization and AI workloads.
Memory and Storage Capacity
The server supports up to 6 TB of DDR5 memory, providing the bandwidth and responsiveness required for data-heavy workloads. Its flexible storage configuration supports up to 36 EDSFF E3.S drives, allowing organizations to scale based on performance or capacity needs. This design makes it ideal for use cases involving large databases, analytics, and unstructured data storage.
GPU and Expansion Support
Designed for performance-driven workloads, the DL345 Gen12 supports multiple GPU configurations, enabling acceleration for AI inference, machine learning, and data visualization tasks. With PCIe Gen5 connectivity, it ensures faster data transfer, reduced latency, and seamless integration with high-speed accelerators and networking cards.
Security and System Management
The DL345 Gen12 integrates HPE Integrated Lights-Out 7 (iLO 7), providing comprehensive server management and advanced security features. iLO 7 offers remote monitoring, system diagnostics, and firmware validation, helping IT teams maintain control and ensure operational reliability. HPE’s silicon root of trust adds a layer of hardware-level protection, safeguarding systems from potential firmware threats.
Energy Efficiency and Cooling
Its 2U air-cooled design balances high performance with efficient thermal management. This design supports consistent operation under demanding workloads while minimizing energy consumption, making it suitable for data centers prioritizing energy efficiency and sustainable operations.
Expansion and Connectivity
The DL345 Gen12 includes multiple PCIe Gen5 slots, allowing faster I/O operations and improved data throughput. These slots support a wide range of networking, storage, and GPU expansion options, ensuring that the system can be easily customized for different enterprise applications.
Performance and Scalability
The HPE ProLiant Compute DL345 Gen12 delivers outstanding compute density and scalability within a single-socket design. Its architecture supports large-scale virtualization clusters, database servers, and AI frameworks with ease. The combination of AMD EPYC performance and high-speed DDR5 memory enables quick data processing for complex applications while maintaining excellent performance-per-watt efficiency.
This platform is engineered to support:
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Virtualization and Hyperconverged Infrastructure - Simplify resource allocation for multiple workloads while maximizing performance.
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AI and Machine Learning - Run GPU-accelerated inference and training models with high efficiency.
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Data Analytics and Databases - Process and store massive datasets quickly for real-time insights.
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Enterprise and Cloud Applications - Support dynamic and mission-critical applications with reliable uptime.
 
Optimized for Data Center Flexibility
The DL345 Gen12 fits seamlessly into both existing and new data center environments. Its modular 2U design allows for easy scalability, while its combination of compute, memory, and storage flexibility ensures readiness for a wide range of enterprise workloads. Organizations can confidently deploy this server to:
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Consolidate multiple workloads efficiently on a single platform.
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Balance performance and power consumption for sustainable operations.
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Scale horizontally across nodes as data and workload needs grow.
 
Availability at eSaitech
The HPE ProLiant Compute DL345 Gen12 is now available at Saitech Inc, offering flexible configurations tailored to meet enterprise performance and storage requirements. Designed for efficiency, reliability, and scalability, it provides a solid foundation for AI, data analytics, and virtualization workloads.
To explore product options or configure your system, visit HPE Gen12 Servers at eSaitech.

              
            