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- Overview
Overview
HPE P75399-B21 ProLiant DL580 Gen12 is a 4U rackmount CTO server supporting up to 4 Intel Xeon 6 processors and 16TB DDR5 across 64 DIMM slots. It features PCIe Gen5 expansion, EDSFF NVMe drive support, TPM 2.0 security, and HPE iLO management for high-performance enterprise workloads.
Specifications
Model Number: P75399-B21
Brand: HPE
Alt Part Number(s): P75399-B21
Product Type: Server
Technical Description
Brand: HPE
Model: P75399-B21
Processor DIMM Slots: Supports up to 4 Intel Xeon 6 processors
Maximum Memory / Slots: Supports up to 16 TB DDR5 using 64 DIMM slots
Heat Sinks: HPE High Performance Heatsinks
Fans: 4 performance fan kits
Drive / Storage Options: Up to 32 EDSFF E3.S drives (for ultra-fast NVMe)
PCIe / Expansion Slots: PCIe Gen5 - up to 12 full‑height / ¾-length slots
I/O Ports (Front): One (1) USB 3.2 Gen1, One (1) USB-C iLO service port, One (1) DisplayPort (optional), Two (2) USB 2.0 (optional via Universal Media Bay)
I/O Ports (Rear): Two (2) USB 3.2 Gen1, One (1) iLO Management Ethernet Port, VGA port, One (1) optional Serial Port
I/O Ports (Internal): One (1) USB 3.2
Security: Embedded TPM 2.0 (Trusted Platform Module), HPE Trusted Supply Chain P36394-B21 – Optional
Rail Kit: Optional Rail Kit and CMA
Form Factor: 4U Rackmount, GPU Servers
Management: HPE iLO with Intelligent Provisioning (standard), iLO Advanced and OneView (optional)
*Product descriptions, images, and part numbers are subject to change and may not accurately reflect manufacturer product alterations. For the latest and most precise information, kindly refer to the manufacturer's website and use the item's manufacturer part number.
